https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33998 Wed 30 Jan 2019 13:35:10 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53434 Wed 28 Feb 2024 15:37:47 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42025 Wed 17 Aug 2022 11:10:20 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:51651 Wed 13 Sep 2023 10:02:53 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12524 Wed 11 Apr 2018 15:30:28 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:30976 Wed 06 Apr 2022 14:00:21 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44964 Tue 25 Oct 2022 13:31:32 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33760 50% seizure reduction, and a trend of better seizure freedom. Their tolerability would also be considered acceptable with the observed low withdrawal rate. However, the relative lack of well-conducted RCTs evaluating their effectiveness against other active AED treatment in children would not facilitate evidence-based practice. This highlights the knowledge gap and the need for more well-conducted RCTs against active treatments to ascertain the long term effectiveness and the role of newer AEDs in managing epilepsy in children.]]> Tue 03 Sep 2019 17:57:39 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:41561 Thu 18 Apr 2024 12:30:28 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48434 75%. This corresponded to an overall reduction in seizure frequency from 32 to 7.2 seizures per month. Ninety-one percent of adverse events were mild or moderate, and none required drug withdrawal. Sixty-two percent were judged to be unrelated to CBDV. Thirty-one percent of adverse events were identified as possibly related, of which nearly all were mild, and the remainder were later assessed as RTT symptoms. Hypersomnolence and drooling were identified as related to CBDV. No serious adverse events reported were related to CBDV. No significant change was noted in EEG or non-epilepsy-related symptoms of RTT. Significance: A dose of 10 mg/kg/day of CBDV is safe and well tolerated in a pediatric RTT cohort and suggests improved seizure control in children with MECP2-related RTT.]]> Thu 16 Mar 2023 14:17:55 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:14527 18 years. Types of intervention(s)/phenomena of interest: Intervention programs were required to have a parental component, to target eating and/or exercise behaviors for the prevention or treatment of obesity, and child weight status reported. Types of studies: All intervention studies were included in the review including: randomized controlled trials (RCTs); non-randomized controlled trials, longitudinal studies, cohort (both retrospective and prospective), case control and time series studies which had been conducted in a community setting. Types of outcomes: This review considered studies that included overweight/obesity related outcomes, eating behavior outcomes, physical activity behaviour outcomes, and sedentary behavior outcomes and constructs. Search strategy: A literature search of community-based parent-centred intervention studies to promote nutrition and physical activity for the prevention and treatment and of childhood overweight and obesity was performed in eight electronic databases dating from 1975 to April 2009. Methodological quality: Studies were critically appraised for methodological quality using standardized tools. Data collection: Data was extracted by one reviewer using a standardized data extraction form developed by the researchers and checked for accuracy and consistency by a second reviewer. Data synthesis: Data in relation to setting, methodology, intervention components and effect on weight, dietary intake and physical activity was extracted, and described in a narrative synthesis. Where possible a meta-analysis was undertaken. Results: Of the home-based interventions, five of nine studies reported statistically significant changes in anthropometric outcomes post intervention. Of the 10 studies in the before and after school care setting, seven reported a significant decrease in a weight-related outcome post intervention, with only one reporting an increase. Conclusions: Results from the review support the after-school setting as the most promising for community intervention setting for targeting parents as agents of change within child obesity prevention and treatment programs.]]> Sat 24 Mar 2018 08:19:46 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12427 2.25) children (33%) had an omega-3 index of < 4.0 (high risk) compared with non-obese children (BMI z-score < 2.25) (17%). Simultaneously, the number of children with a higher omega-3 index (6.0–8.0 lower risk) was lower in the obese (13%) versus non-obese children (25%, respectively). A moderate, but statistically significant correlation was found between O3I and fasting insulin level (r = −0.3, P = 0.03) and with homeostatic model assessment (HOMA) scores (r = −0.3, P = 0.04). Conclusion: The observed association between the omega-3 index, weight status and insulin resistance in children highlights the importance of omega-3 fatty acids in the prevention of obesity-related chronic diseases in later life. The results presented merits confirmation in a larger sample of obese children.]]> Sat 24 Mar 2018 08:17:46 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:10860 Sat 24 Mar 2018 08:12:05 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:17379 Sat 24 Mar 2018 08:01:31 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20903 Sat 24 Mar 2018 07:57:53 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19720 p < 0.001). GI was negatively and independently related to ¹³CISS in boys (β = −0.195, p < 0.05) but not in girls. Other dietary variables were not associated with IS. In addition to BMI z score, a low GI diet predicted ¹³CISS in boys but not in girls. This finding suggests that interventions that reduce BMI (in both sexes) and include a low GI diet among boys may improve IS.]]> Sat 24 Mar 2018 07:53:43 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:5328 0.05). Total quantity of food (g) and kJ kg⁻¹ decreased significantly at both time points (P<0.05). Percent energy derived from core food groups, except fruit, increased significantly at 12 months compared to baseline (P<0.05), and non-core foods decreased, with the largest decreases being for sweetened drinks (5.0±0.4 vs 2.9±0.3% of energy baseline to 12 months, P<0.001) and packaged lunch box snacks (5.4±0.3 vs 4.1±0.3% of energy baseline to 12 months, P<0.001). Conclusion: All treatment groups in the HIKCUPS study appear to be equally efficacious in improving dietary intake in overweight and obese children.]]> Sat 24 Mar 2018 07:45:56 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:5388 Sat 24 Mar 2018 07:43:55 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:25714 Sat 24 Mar 2018 07:33:28 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:37729 Mon 29 Mar 2021 10:56:53 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48482 Mon 20 Mar 2023 10:27:49 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19772 Fri 29 May 2020 17:14:37 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53880 Fri 19 Jan 2024 12:44:57 AEDT ]]>